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iCFN: an efficient exact algorithm for multistate protein design

MOTIVATION: Multistate protein design addresses real-world challenges, such as multi-specificity design and backbone flexibility, by considering both positive and negative protein states with an ensemble of substates for each. It also presents an enormous challenge to exact algorithms that guarantee...

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Detalles Bibliográficos
Autores principales: Karimi, Mostafa, Shen, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129278/
https://www.ncbi.nlm.nih.gov/pubmed/30423073
http://dx.doi.org/10.1093/bioinformatics/bty564