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Single cell network analysis with a mixture of Nested Effects Models

MOTIVATION: New technologies allow for the elaborate measurement of different traits of single cells under genetic perturbations. These interventional data promise to elucidate intra-cellular networks in unprecedented detail and further help to improve treatment of diseases like cancer. However, cel...

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Detalles Bibliográficos
Autores principales: Pirkl, Martin, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129288/
https://www.ncbi.nlm.nih.gov/pubmed/30423100
http://dx.doi.org/10.1093/bioinformatics/bty602