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iTOP: inferring the topology of omics data

MOTIVATION: In biology, we are often faced with multiple datasets recorded on the same set of objects, such as multi-omics and phenotypic data of the same tumors. These datasets are typically not independent from each other. For example, methylation may influence gene expression, which may, in turn,...

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Detalles Bibliográficos
Autores principales: Aben, Nanne, Westerhuis, Johan A, Song, Yipeng, Kiers, Henk A L, Michaut, Magali, Smilde, Age K, Wessels, Lodewyk F A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129292/
https://www.ncbi.nlm.nih.gov/pubmed/30423084
http://dx.doi.org/10.1093/bioinformatics/bty636