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Inference of the human polyadenylation code

MOTIVATION: Processing of transcripts at the 3′-end involves cleavage at a polyadenylation site followed by the addition of a poly(A)-tail. By selecting which site is cleaved, the process of alternative polyadenylation enables genes to produce transcript isoforms with different 3′-ends. To facilitat...

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Detalles Bibliográficos
Autores principales: Leung, Michael K K, Delong, Andrew, Frey, Brendan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129302/
https://www.ncbi.nlm.nih.gov/pubmed/29648582
http://dx.doi.org/10.1093/bioinformatics/bty211