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SYKT Alleviates Doxorubicin-Induced Cardiotoxicity via Modulating ROS-Mediated p53 and MAPK Signal Pathways

Backgrounds. Doxorubicin (DOX) is an effective therapeutic drug for malignant tumors; however, its clinical applications were limited by its side effects, especially the cardiotoxicity caused by ROS-mediated p53 and MAPK signal pathways' activation-induced cell apoptosis. Sanyang Xuedai mixture...

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Detalles Bibliográficos
Autores principales: Chen, Ting, Deng, Zhiyong, Zhao, Ruilian, Shen, Hongmei, Li, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129364/
https://www.ncbi.nlm.nih.gov/pubmed/30224925
http://dx.doi.org/10.1155/2018/2581031