Cargando…

SYKT Alleviates Doxorubicin-Induced Cardiotoxicity via Modulating ROS-Mediated p53 and MAPK Signal Pathways

Backgrounds. Doxorubicin (DOX) is an effective therapeutic drug for malignant tumors; however, its clinical applications were limited by its side effects, especially the cardiotoxicity caused by ROS-mediated p53 and MAPK signal pathways' activation-induced cell apoptosis. Sanyang Xuedai mixture...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ting, Deng, Zhiyong, Zhao, Ruilian, Shen, Hongmei, Li, Wenhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129364/ https://www.ncbi.nlm.nih.gov/pubmed/30224925 http://dx.doi.org/10.1155/2018/2581031

Ejemplares similares

A herbal formula, SYKT, reverses doxorubicin-induced myelosuppression and cardiotoxicity by inhibiting ROS-mediated apoptosis
por: Chen, Ting, et al.
Publicado: (2017)

Cinnamaldehyde alleviates doxorubicin-induced cardiotoxicity by decreasing oxidative stress and ferroptosis in cardiomyocytes
por: Mao, Meijiao, et al.
Publicado: (2023)

Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27
por: Bernard, Yohann, et al.
Publicado: (2011)

Klotho Improves Cardiac Function by Suppressing Reactive Oxygen Species (ROS) Mediated Apoptosis by Modulating Mapks/Nrf2 Signaling in Doxorubicin-Induced Cardiotoxicity
por: Zhu, Huolan, et al.
Publicado: (2017)

RRM2 Alleviates Doxorubicin-Induced Cardiotoxicity through the AKT/mTOR Signaling Pathway
por: Jiao, Yuheng, et al.
Publicado: (2022)

Oleoylethanolamide as a New Therapeutic Strategy to Alleviate Doxorubicin-Induced Cardiotoxicity
por: Qin, Yeyu, et al.
Publicado: (2022)

Pristimerin protects against doxorubicin-induced cardiotoxicity and fibrosis through modulation of Nrf2 and MAPK/NF-kB signaling pathways
por: El-Agamy, Dina S, et al.
Publicado: (2018)

Nerolidol Attenuates Oxidative Stress, Inflammation, and Apoptosis by Modulating Nrf2/MAPK Signaling Pathways in Doxorubicin-Induced Acute Cardiotoxicity in Rats
por: Arunachalam, Seenipandi, et al.
Publicado: (2021)

Astragalus Polysaccharide Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the PI3k/Akt and p38MAPK Pathways
por: Cao, Yuan, et al.
Publicado: (2014)

Rosmarinic acid alleviates cardiomyocyte apoptosis via cardiac fibroblast in doxorubicin-induced cardiotoxicity
por: Zhang, Xin, et al.
Publicado: (2019)

WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis
por: Tai, Panpan, et al.
Publicado: (2023)

Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin
por: Hou, Kai, et al.
Publicado: (2021)

TLR9 deficiency alleviates doxorubicin‐induced cardiotoxicity via the regulation of autophagy
por: Guo, Zhen, et al.
Publicado: (2020)

Piperine Alleviates Doxorubicin-Induced Cardiotoxicity via Activating PPAR-γ in Mice
por: Yan, Jie, et al.
Publicado: (2019)

Breviscapine remodels myocardial glucose and lipid metabolism by regulating serotonin to alleviate doxorubicin-induced cardiotoxicity
por: Li, Meng-Jiao, et al.
Publicado: (2022)

Peptide Szeto-Schiller 31 ameliorates doxorubicin-induced cardiotoxicity by inhibiting the activation of the p38 MAPK signaling pathway
por: Zhang, Li, et al.
Publicado: (2021)

Regulated cell death pathways in doxorubicin-induced cardiotoxicity
por: Christidi, Effimia, et al.
Publicado: (2021)

miR-146a attenuates apoptosis and modulates autophagy by targeting TAF9b/P53 pathway in doxorubicin-induced cardiotoxicity
por: Pan, Jian-An, et al.
Publicado: (2019)

Calycosin Alleviates Doxorubicin-Induced Cardiotoxicity and Pyroptosis by Inhibiting NLRP3 Inflammasome Activation
por: Zhang, Lei, et al.
Publicado: (2022)

INKing the Cardiotoxicity Out of Doxorubicin
por: Guo, Zhen, et al.
Publicado: (2023)

Transcriptomic profiling reveals p53 as a key regulator of doxorubicin-induced cardiotoxicity
por: McSweeney, K. Melodi, et al.
Publicado: (2019)

FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT
por: Zhang, Xin, et al.
Publicado: (2019)

DDX3X alleviates doxorubicin‐induced cardiotoxicity by regulating Wnt/β‐catenin signaling pathway in an in vitro model
por: Feng, Dandan, et al.
Publicado: (2022)

Desferrioxamine Attenuates Doxorubicin-Induced Acute Cardiotoxicity through TFG-β/Smad p53 Pathway in Rat Model
por: Al-Shabanah, Othman A., et al.
Publicado: (2012)

Levosimendan Protects against Doxorubicin-Induced Cardiotoxicity by Regulating the PTEN/Akt Pathway
por: Li, Ling-Li, et al.
Publicado: (2020)

Mesaconine alleviates doxorubicin-triggered cardiotoxicity and heart failure by activating PINK1-dependent cardiac mitophagy
por: Zhou, Ji-Chao, et al.
Publicado: (2023)

Setanaxib (GKT137831) Ameliorates Doxorubicin-Induced Cardiotoxicity by Inhibiting the NOX1/NOX4/Reactive Oxygen Species/MAPK Pathway
por: Zheng, Hui, et al.
Publicado: (2022)

Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy
por: Li, Weili, et al.
Publicado: (2022)

p53 at the Crossroads between Doxorubicin-Induced Cardiotoxicity and Resistance: A Nutritional Balancing Act
por: Guo, Yuanfang, et al.
Publicado: (2023)

Albumin-Based Zn (II)-Quercetin Enzyme Mimic Scavenging ROS for Protection against Cardiotoxicity Induced by Doxorubicin
por: Shao, Zehua, et al.
Publicado: (2022)

Role of acetylation in doxorubicin-induced cardiotoxicity
por: Li, Daisong, et al.
Publicado: (2021)

Dipyridamole ameliorates doxorubicin-induced cardiotoxicity
por: Alyasiry, Esraa, et al.
Publicado: (2022)

Luteolin attenuates doxorubicin-induced cardiotoxicity by modulating the PHLPP1/AKT/Bcl-2 signalling pathway
por: Zhang, YanDong, et al.
Publicado: (2020)

Mokko Lactone Alleviates Doxorubicin-Induced Cardiotoxicity in Rats via Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities
por: Sirwi, Alaa, et al.
Publicado: (2022)

Trophoblast Stem-Cell-Derived Exosomes Alleviate Cardiotoxicity of Doxorubicin via Improving Mfn2-Mediated Mitochondrial Fusion
por: Duan, Junfeng, et al.
Publicado: (2023)

Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression
por: Xu, Fan, et al.
Publicado: (2017)

Myricitrin Protects against Doxorubicin-Induced Cardiotoxicity by Counteracting Oxidative Stress and Inhibiting Mitochondrial Apoptosis via ERK/P53 Pathway
por: Sun, Jing, et al.
Publicado: (2016)

Cilostazol alleviate nicotine induced cardiomyocytes hypertrophy through modulation of autophagy by CTSB/ROS/p38MAPK/JNK feedback loop
por: Wang, Shu-ya, et al.
Publicado: (2020)

Morphine Enhances Doxorubicin-Induced Cardiotoxicity in the Rat
por: Hole, Lisa Drange, et al.
Publicado: (2014)

The true colors of autophagy in doxorubicin-induced cardiotoxicity
por: Xiao, Bin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vv66vdpdnu569mv2fgjf3b70el