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Icaritin Provokes Serum Thrombopoietin and Downregulates Thrombopoietin/MPL of the Bone Marrow in a Mouse Model of Immune Thrombocytopenia

Immune thrombocytopenia (ITP) is a common acquired autoimmune disease, and thrombopoietin (TPO) is an important cytokine that regulates the production of megakaryocytes and platelets. We have identified a biologically active component, icaritin, from a Chinese herba epimedii extract. Icaritin promot...

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Detalles Bibliográficos
Autores principales: Zhang, Ke, Dai, Zhenfeng, Liu, Runzhe, Tian, Fang, Liu, Xi, Sun, Yi, Zhao, Xin, Pu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129856/
https://www.ncbi.nlm.nih.gov/pubmed/30224899
http://dx.doi.org/10.1155/2018/7235639