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Icaritin Provokes Serum Thrombopoietin and Downregulates Thrombopoietin/MPL of the Bone Marrow in a Mouse Model of Immune Thrombocytopenia
Immune thrombocytopenia (ITP) is a common acquired autoimmune disease, and thrombopoietin (TPO) is an important cytokine that regulates the production of megakaryocytes and platelets. We have identified a biologically active component, icaritin, from a Chinese herba epimedii extract. Icaritin promot...
Autores principales: | Zhang, Ke, Dai, Zhenfeng, Liu, Runzhe, Tian, Fang, Liu, Xi, Sun, Yi, Zhao, Xin, Pu, Xiaoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129856/ https://www.ncbi.nlm.nih.gov/pubmed/30224899 http://dx.doi.org/10.1155/2018/7235639 |
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