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Synthetic circuits reveal how mechanisms of gene regulatory networks constrain evolution

Phenotypic variation is the raw material of adaptive Darwinian evolution. The phenotypic variation found in organismal development is biased towards certain phenotypes, but the molecular mechanisms behind such biases are still poorly understood. Gene regulatory networks have been proposed as one cau...

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Detalles Bibliográficos
Autores principales: Schaerli, Yolanda, Jiménez, Alba, Duarte, José M, Mihajlovic, Ljiljana, Renggli, Julien, Isalan, Mark, Sharpe, James, Wagner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129954/
https://www.ncbi.nlm.nih.gov/pubmed/30201776
http://dx.doi.org/10.15252/msb.20178102