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A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA

Genomes are promiscuously transcribed, necessitating mechanisms that facilitate the sorting of RNA for function or destruction. The polyA (pA) tail is one such distinguishing feature, which in the Saccharomyces cerevisiae nucleus is bound by the Nab2p protein, yielding transcript protection. As Nab2...

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Detalles Bibliográficos
Autores principales: Tudek, Agnieszka, Schmid, Manfred, Makaras, Marius, Barrass, J. David, Beggs, Jean D., Jensen, Torben Heick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130047/
https://www.ncbi.nlm.nih.gov/pubmed/30157437
http://dx.doi.org/10.1016/j.celrep.2018.07.103