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Behavioural phenotyping, learning and memory in young and aged growth hormone-releasing hormone-knockout mice

BACKGROUND: Growth hormone-releasing hormone (GHRH) plays an important role in brain functions. The aim of this study was to examine cognitive functions and emotional behaviour in a mouse model of isolated GH deficiency due to bi-allelic ablation of the GHRH gene (GHRH knockout, GHRHKO). METHODS: Le...

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Detalles Bibliográficos
Autores principales: Leone, Sheila, Recinella, Lucia, Chiavaroli, Annalisa, Ferrante, Claudio, Orlando, Giustino, Vacca, Michele, Salvatori, Roberto, Brunetti, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130317/
https://www.ncbi.nlm.nih.gov/pubmed/30300535
http://dx.doi.org/10.1530/EC-18-0165