Cargando…

Behavioural phenotyping, learning and memory in young and aged growth hormone-releasing hormone-knockout mice

BACKGROUND: Growth hormone-releasing hormone (GHRH) plays an important role in brain functions. The aim of this study was to examine cognitive functions and emotional behaviour in a mouse model of isolated GH deficiency due to bi-allelic ablation of the GHRH gene (GHRH knockout, GHRHKO). METHODS: Le...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leone, Sheila, Recinella, Lucia, Chiavaroli, Annalisa, Ferrante, Claudio, Orlando, Giustino, Vacca, Michele, Salvatori, Roberto, Brunetti, Luigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130317/ https://www.ncbi.nlm.nih.gov/pubmed/30300535 http://dx.doi.org/10.1530/EC-18-0165

Ejemplares similares

SUN-117 Growth Hormone-Releasing Hormone (GHRH) Deficiency Promotes Inflammation Associated Carcinogenesis
por: Recinella, PharmD, Lucia, et al.
Publicado: (2020)

Antinflammatory, antioxidant, and behavioral effects induced by administration of growth hormone-releasing hormone analogs in mice
por: Recinella, Lucia, et al.
Publicado: (2020)

Publisher Correction: Antinflammatory, antioxidant, and behavioral effects induced by administration of growth hormone-releasing hormone analogs in mice
por: Recinella, Lucia, et al.
Publicado: (2020)

Protective effects of growth hormone-releasing hormone analogs in DSS-induced colitis in mice
por: Recinella, Lucia, et al.
Publicado: (2021)

SAT-603 Growth Hormone-Releasing Hormone (GHRH) Antagonists Stimulate Feeding in Mice
por: Leone, Sheila, et al.
Publicado: (2020)

Adipokines: New Potential Therapeutic Target for Obesity and Metabolic, Rheumatic, and Cardiovascular Diseases
por: Recinella, Lucia, et al.
Publicado: (2020)

Inhibitory Effects Induced by Vicia faba, Uncaria rhyncophylla, and Glycyrrhiza glabra Water Extracts on Oxidative Stress Biomarkers and Dopamine Turnover in HypoE22 Cells and Isolated Rat Striatum Challenged with 6-Hydroxydopamine
por: Orlando, Giustino, et al.
Publicado: (2019)

MON-478 Antinflammatory and Antioxidant Effects of MIA-690 and MR-409 in GHRHKO Mice Colon and Prefrontal Cortex
por: Leone, Sheila, et al.
Publicado: (2019)

Protective Effects Induced by Two Polyphenolic Liquid Complexes from Olive (Olea europaea, mainly Cultivar Coratina) Pressing Juice in Rat Isolated Tissues Challenged with LPS
por: Recinella, Lucia, et al.
Publicado: (2019)

Neuroprotective and Neuromodulatory Effects Induced by Cannabidiol and Cannabigerol in Rat Hypo-E22 cells and Isolated Hypothalamus
por: di Giacomo, Viviana, et al.
Publicado: (2020)

Effects of Kisspeptin-10 on Hypothalamic Neuropeptides and Neurotransmitters Involved in Appetite Control
por: Orlando, Giustino, et al.
Publicado: (2018)

Phenolic Characterization and Neuroprotective Properties of Grape Pomace Extracts
por: Chiavaroli, Annalisa, et al.
Publicado: (2021)

Graminex Pollen: Phenolic Pattern, Colorimetric Analysis and Protective Effects in Immortalized Prostate Cells (PC3) and Rat Prostate Challenged with LPS
por: Locatelli, Marcello, et al.
Publicado: (2018)

Anti-Inflammatory Effects Induced by a Polyphenolic Granular Complex from Olive (Olea europaea, Mainly Cultivar coratina): Results from In Vivo and Ex Vivo Studies in a Model of Inflammation and MIA-Induced Osteoarthritis
por: Recinella, Lucia, et al.
Publicado: (2022)

Shedding Light into the Connection between Chemical Components and Biological Effects of Extracts from Epilobium hirsutum: Is It a Potent Source of Bioactive Agents from Natural Treasure?
por: Ak, Gunes, et al.
Publicado: (2021)

Anti-Inflammatory and Neuromodulatory Effects Induced by Tanacetum parthenium Water Extract: Results from In Silico, In Vitro and Ex Vivo Studies
por: Recinella, Lucia, et al.
Publicado: (2020)

Effects of GHRH Deficiency and GHRH Antagonism on Emotional Disorders in Mice
por: Recinella, Lucia, et al.
Publicado: (2023)

Qualitative Phytochemical Fingerprint and Network Pharmacology Investigation of Achyranthes aspera Linn. Extracts
por: Sinan, Kouadio Ibrahime, et al.
Publicado: (2020)

Protective Effects of PollenAid Plus Soft Gel Capsules’ Hydroalcoholic Extract in Isolated Prostates and Ovaries Exposed to Lipopolysaccharide
por: Chiavaroli, Annalisa, et al.
Publicado: (2022)

Antioxidant and Neuroprotective Effects Induced by Cannabidiol and Cannabigerol in Rat CTX-TNA2 Astrocytes and Isolated Cortexes
por: di Giacomo, Viviana, et al.
Publicado: (2020)

Antimicrobial, Antioxidant, and Antiproliferative Effects of Coronilla minima: An Unexplored Botanical Species
por: Ferrante, Claudio, et al.
Publicado: (2020)

Evaluation of Antioxidant, Antimicrobial and Tyrosinase Inhibitory Activities of Extracts from Tricholosporum goniospermum, an Edible Wild Mushroom
por: Angelini, Paola, et al.
Publicado: (2020)

Phenolic Content and Antimicrobial and Anti-Inflammatory Effects of Solidago virga-aurea, Phyllanthus niruri, Epilobium angustifolium, Peumus boldus, and Ononis spinosa Extracts
por: Ferrante, Claudio, et al.
Publicado: (2020)

A grape (Vitis vinifera L.) pomace water extract modulates inflammatory and immune response in SW‐480 cells and isolated mouse colon
por: Recinella, Lucia, et al.
Publicado: (2022)

Phytochemical Analysis, Network Pharmacology and in Silico Investigations on Anacamptis pyramidalis Tuber Extracts
por: Fawzi Mahomoodally, Mohamad, et al.
Publicado: (2020)

Anti-Inflammatory, Antioxidant, and WAT/BAT-Conversion Stimulation Induced by Novel PPAR Ligands: Results from Ex Vivo and In Vitro Studies
por: Recinella, Lucia, et al.
Publicado: (2023)

Anti-Inflammatory and Vasorelaxant Effects Induced by an Aqueous Aged Black Garlic Extract Supplemented with Vitamins D, C, and B12 on Cardiovascular System
por: Recinella, Lucia, et al.
Publicado: (2023)

Screening for Chemical Characterization and Pharmacological Properties of Different Extracts from Nepeta italica
por: Acquaviva, Alessandra, et al.
Publicado: (2023)

Qualitative Chemical Characterization and Multidirectional Biological Investigation of Leaves and Bark Extracts of Anogeissus leiocarpus (DC.) Guill. & Perr. (Combretaceae)
por: Orlando, Giustino, et al.
Publicado: (2019)

Chemical Composition and Biological Properties of Two Jatropha Species: Different Parts and Different Extraction Methods
por: Zengin, Gokhan, et al.
Publicado: (2021)

Comprehensive Chemical Profiling and Multidirectional Biological Investigation of Two Wild Anthemis Species (Anthemis tinctoria var. Pallida and A. cretica subsp. tenuiloba): Focus on Neuroprotective Effects
por: Orlando, Giustino, et al.
Publicado: (2019)

Biopotential of Bersama abyssinica Fresen Stem Bark Extracts: UHPLC Profiles, Antioxidant, Enzyme Inhibitory, and Antiproliferative Propensities
por: Sinan, Kouadio Ibrahime, et al.
Publicado: (2020)

Evaluation of Pharmacological and Phytochemical Profiles of Piptadeniastrum africanum (Hook.f.) Brenan Stem Bark Extracts
por: Sinan, Kouadio Ibrahime, et al.
Publicado: (2020)

Unravelling the Phytochemical Composition and the Pharmacological Properties of an Optimized Extract from the Fruit from Prunus mahaleb L.: From Traditional Liqueur Market to the Pharmacy Shelf
por: Orlando, Giustino, et al.
Publicado: (2021)

Comparative Investigation of Composition, Antifungal, and Anti-Inflammatory Effects of the Essential Oil from Three Industrial Hemp Varieties from Italian Cultivation
por: Orlando, Giustino, et al.
Publicado: (2021)

Adding New Scientific Evidences on the Pharmaceutical Properties of Pelargonium quercetorum Agnew Extracts by Using In Vitro and In Silico Approaches
por: Chiavaroli, Annalisa, et al.
Publicado: (2023)

Multidirectional Pharma-Toxicological Study on Harpagophytum procumbens DC. ex Meisn.: An IBD-Focused Investigation
por: Recinella, Lucia, et al.
Publicado: (2020)

Deeper Insights on Alchornea cordifolia (Schumach. & Thonn.) Müll.Arg Extracts: Chemical Profiles, Biological Abilities, Network Analysis and Molecular Docking
por: Sinan, Kouadio Ibrahime, et al.
Publicado: (2021)

Metabolomic Profile and Antioxidant/Anti-Inflammatory Effects of Industrial Hemp Water Extract in Fibroblasts, Keratinocytes and Isolated Mouse Skin Specimens
por: di Giacomo, Viviana, et al.
Publicado: (2021)

Protective Effects Induced by a Hydroalcoholic Allium sativum Extract in Isolated Mouse Heart
por: Recinella, Lucia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_501tnmii0ofal7a37pg33bkt3t