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High-pressure protein crystal structure analysis of Escherichia coli dihydrofolate reductase complexed with folate and NADP(+)
A high-pressure crystallographic study was conducted on Escherichia coli dihydrofolate reductase (ecDHFR) complexed with folate and NADP(+) in crystal forms containing both the open and closed conformations of the M20 loop under high-pressure conditions of up to 800 MPa. At pressures between 270 and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130465/ https://www.ncbi.nlm.nih.gov/pubmed/30198899 http://dx.doi.org/10.1107/S2059798318009397 |