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Detection and characterization of the metabolites of rutaecarpine in rats based on ultra-high-performance liquid chromatography with linear ion trap-Orbitrap mass spectrometer

Context: Rutaecarpine is an active indoloquinazoline alkaloid ingredient originating from Evodia rutaecarpa (Wu-zhu-yu in Chinese), which possesses a variety of effects. However, its metabolism has not been investigated thoroughly yet. Objective: This study develops a highly sensitive and effective...

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Detalles Bibliográficos
Autores principales: Cai, Wei, Guan, Ying, Zhou, Yang, Wang, Yuwei, Ji, Huaiping, Liu, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130507/
https://www.ncbi.nlm.nih.gov/pubmed/27927077
http://dx.doi.org/10.1080/13880209.2016.1236392