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Functional and structural connectome properties in the 5XFAD transgenic mouse model of Alzheimer’s disease

Neurodegeneration in Alzheimer’s disease (AD) is associated with amyloid-beta peptide accumulation into insoluble amyloid plaques. The five-familial AD (5XFAD) transgenic mouse model exhibits accelerated amyloid-beta deposition, neuronal dysfunction, and cognitive impairment. We aimed to determine w...

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Detalles Bibliográficos
Autores principales: Kesler, Shelli R., Acton, Paul, Rao, Vikram, Ray, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MIT Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130552/
https://www.ncbi.nlm.nih.gov/pubmed/30215035
http://dx.doi.org/10.1162/netn_a_00048