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Functional and structural connectome properties in the 5XFAD transgenic mouse model of Alzheimer’s disease
Neurodegeneration in Alzheimer’s disease (AD) is associated with amyloid-beta peptide accumulation into insoluble amyloid plaques. The five-familial AD (5XFAD) transgenic mouse model exhibits accelerated amyloid-beta deposition, neuronal dysfunction, and cognitive impairment. We aimed to determine w...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MIT Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130552/ https://www.ncbi.nlm.nih.gov/pubmed/30215035 http://dx.doi.org/10.1162/netn_a_00048 |