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Effects of Ginkgo leaf tablets on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism

Context: Ginkgo leaf tablets (GLTs) and losartan are often simultaneously used for the treatment of hypertension in Chinese clinics. However, the herb–drug interaction between GLT and losartan is still unknown. Objective: This study investigates the effects of GLT on the pharmacokinetics of losartan...

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Detalles Bibliográficos
Autores principales: Dong, Baiping, Yuan, Suowei, Hu, Jinsheng, Yan, Yanzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130633/
https://www.ncbi.nlm.nih.gov/pubmed/29953302
http://dx.doi.org/10.1080/13880209.2018.1481107