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Effects of Ginkgo leaf tablets on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism
Context: Ginkgo leaf tablets (GLTs) and losartan are often simultaneously used for the treatment of hypertension in Chinese clinics. However, the herb–drug interaction between GLT and losartan is still unknown. Objective: This study investigates the effects of GLT on the pharmacokinetics of losartan...
Autores principales: | Dong, Baiping, Yuan, Suowei, Hu, Jinsheng, Yan, Yanzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130633/ https://www.ncbi.nlm.nih.gov/pubmed/29953302 http://dx.doi.org/10.1080/13880209.2018.1481107 |
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