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Determination of cepharanthine in rat plasma by LC–MS/MS and its application to a pharmacokinetic study

Context: Cepharanthine (CPA) has been reported to possess a wide range of pharmacological activities. Objective: This study investigates the pharmacokinetic characteristics after oral or intravenous administration of CPA by using a sensitive and rapid LC–MS/MS method. Materials and methods: A sensit...

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Detalles Bibliográficos
Autores principales: Deng, Yingbin, Wu, Weijun, Ye, Sunzhi, Wang, Wei, Wang, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130670/
https://www.ncbi.nlm.nih.gov/pubmed/28521597
http://dx.doi.org/10.1080/13880209.2017.1328446