Metformin attenuates hepatic insulin resistance in type-2 diabetic rats through PI3K/Akt/GLUT-4 signalling independent to bicuculline-sensitive GABA(A) receptor stimulation

Context: Metformin attenuates type-2 diabetes mellitus (T2DM)-induced hepatic dysfunction and altered PI3K/Akt/GLUT-4 signalling in experimental studies. However, its effect on bicuculline-sensitive gamma amino butyric acid (GABA)-A receptor (GABA(A)R)-mediated calcium-dependent PI3K/Akt/GLUT-4 sign...

Descripción completa

Detalles Bibliográficos
Autores principales: Garabadu, Debapriya, Krishnamurthy, Sairam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130720/
https://www.ncbi.nlm.nih.gov/pubmed/28142314
http://dx.doi.org/10.1080/13880209.2016.1268635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130720/
https://www.ncbi.nlm.nih.gov/pubmed/28142314
http://dx.doi.org/10.1080/13880209.2016.1268635

Ejemplares similares