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Metformin attenuates hepatic insulin resistance in type-2 diabetic rats through PI3K/Akt/GLUT-4 signalling independent to bicuculline-sensitive GABA(A) receptor stimulation

Context: Metformin attenuates type-2 diabetes mellitus (T2DM)-induced hepatic dysfunction and altered PI3K/Akt/GLUT-4 signalling in experimental studies. However, its effect on bicuculline-sensitive gamma amino butyric acid (GABA)-A receptor (GABA(A)R)-mediated calcium-dependent PI3K/Akt/GLUT-4 sign...

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Detalles Bibliográficos
Autores principales:	Garabadu, Debapriya, Krishnamurthy, Sairam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130720/ https://www.ncbi.nlm.nih.gov/pubmed/28142314 http://dx.doi.org/10.1080/13880209.2016.1268635

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