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Exploring Selectivity of Multikinase Inhibitors across the Human Kinome
[Image: see text] Selectivity of kinase inhibitors, or the lack thereof, continues to be an intensely debated topic in drug discovery research. Especially, type I inhibitors, which represent most of the currently available kinase inhibitors, are often thought to lack selectivity because they target...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130781/ https://www.ncbi.nlm.nih.gov/pubmed/30221217 http://dx.doi.org/10.1021/acsomega.7b01960 |