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Effects of RNA Splicing Inhibitors on Amyloid Precursor Protein Expression

[Image: see text] U1 small ribonucleoproteins demonstrate proteopathy in Alzheimer’s disease, and their inhibition modulates the expression of the amyloid precursor protein (APP). We sought to determine whether this effect on the APP expression is a universal result of different kinds of RNA splicin...

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Detalles Bibliográficos
Autores principales: Bai, Bing, Wang, Sen, Chen, Yuxin, Jia, Jia, Tian, Xinyu, Liu, Chang, Xia, Yanyan, Xie, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130791/
https://www.ncbi.nlm.nih.gov/pubmed/30221221
http://dx.doi.org/10.1021/acsomega.7b02073