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Phosphatase CDC25B Inhibitors Produced by Basic Alumina-Supported One-Pot Gram-Scale Synthesis of Fluorinated 2-Alkylthio-4-aminoquinazolines Using Microwave Irradiation

[Image: see text] An efficient, environmentally benign, and inexpensive procedure has been developed for the synthesis of fluorinated 2-alkylthio-4-aminoquinazolines by microwave irradiation using basic alumina as a solid-support agent as well as a solid base. Notably, this protocol features improve...

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Detalles Bibliográficos
Autores principales: Liu, Jin, Wang, Yu-Ling, Zhang, Ji-Hong, Yang, Jian-Shan, Mou, Han-Chuan, Lin, Jun, Yan, Sheng-Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130795/
https://www.ncbi.nlm.nih.gov/pubmed/30221227
http://dx.doi.org/10.1021/acsomega.8b00640