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Hindsiipropane B alleviates HIV-1 Tat-induced inflammatory responses by suppressing HDAC6-NADPH oxidase-ROS axis in astrocytes

Human immunodeficiency virus-1 (HIV-1) transactivator of transcription (Tat) is an important viral factor in neuroinflammation. Hindsiipropane B, present in Celastrus hindsii, possesses various biological mechanisms including anti-inflammatory activity. In this report, we explored the regulatory act...

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Detalles Bibliográficos
Autores principales: Jo, Hyundong, Jang, Ha Young, Youn, Gi Soo, Kim, Donggyu, Lee, Chae Yeon, Jang, Jae Hee, Choi, Soo Young, Jun, Jong-Gab, Park, Jinseu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130829/
https://www.ncbi.nlm.nih.gov/pubmed/29699604
http://dx.doi.org/10.5483/BMBRep.2018.51.8.061