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Fluorescence-based tools to probe G-quadruplexes in cell-free and cellular environments

Biophysical and biochemical investigations provide compelling evidence connecting the four-stranded G-quadruplex (GQ) structure with its role in regulating multiple cellular processes. Hence, modulating the function of GQs by using small molecule binders is being actively pursued as a strategy to de...

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Detalles Bibliográficos
Autores principales: Manna, Sudeshna, Srivatsan, Seergazhi G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130854/
https://www.ncbi.nlm.nih.gov/pubmed/30210793
http://dx.doi.org/10.1039/c8ra03708f