Overexpression of CD44 Standard Isoform Upregulates HIF-1α Signaling in Hypoxic Breast Cancer Cells

Cluster of differentiation 44 (CD44), a cell surface receptor for hyaluronic acid (HA), is involved in aggressive cancer phenotypes. Herein, we investigated the role of the CD44 standard isoform (CD44s) in hypoxia-inducible factor-1α (HIF-1α) regulation using MCF7 overexpressing CD44s (pCD44s-MCF7)....

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Detalles Bibliográficos
Autores principales: Ryu, Dayoung, Ryoo, In-geun, Kwak, Mi-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131012/
https://www.ncbi.nlm.nih.gov/pubmed/30157616
http://dx.doi.org/10.4062/biomolther.2018.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131012/
https://www.ncbi.nlm.nih.gov/pubmed/30157616
http://dx.doi.org/10.4062/biomolther.2018.116

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