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Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years

To compare clonal evolution in tumors arising through different mechanisms, we selected three types of sarcoma—amplicon-driven well-differentiated liposarcoma (WDLS), gene fusion-driven myxoid liposarcoma (MLS), and sarcomas with complex genomes (CXS)—and assessed the dynamics of chromosome and nucl...

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Detalles Bibliográficos
Autores principales: Hofvander, Jakob, Viklund, Björn, Isaksson, Anders, Brosjö, Otte, Vult von Steyern, Fredrik, Rissler, Pehr, Mandahl, Nils, Mertens, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131146/
https://www.ncbi.nlm.nih.gov/pubmed/30201954
http://dx.doi.org/10.1038/s41467-018-06098-0