Adjunctive use of celecoxib with anti-tuberculosis drugs: evaluation in a whole-blood bactericidal activity model

COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. We investigated celecoxib (a COX-2 inhibitor) alone and with s...

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Detalles Bibliográficos
Autores principales: Naftalin, Claire M., Verma, Rupangi, Gurumurthy, Meera, Hee, Kim Hor, Lu, Qingshu, Yeo, Benjamin Chaik Meng, Tan, Kin Hup, Lin, Wenwei, Yu, Buduo, Seng, Kok Yong, Lee, Lawrence Soon-U, Paton, Nicholas I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131161/
https://www.ncbi.nlm.nih.gov/pubmed/30202030
http://dx.doi.org/10.1038/s41598-018-31590-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131161/
https://www.ncbi.nlm.nih.gov/pubmed/30202030
http://dx.doi.org/10.1038/s41598-018-31590-4

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