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Adjunctive use of celecoxib with anti-tuberculosis drugs: evaluation in a whole-blood bactericidal activity model
COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. We investigated celecoxib (a COX-2 inhibitor) alone and with s...
Autores principales: | Naftalin, Claire M., Verma, Rupangi, Gurumurthy, Meera, Hee, Kim Hor, Lu, Qingshu, Yeo, Benjamin Chaik Meng, Tan, Kin Hup, Lin, Wenwei, Yu, Buduo, Seng, Kok Yong, Lee, Lawrence Soon-U, Paton, Nicholas I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131161/ https://www.ncbi.nlm.nih.gov/pubmed/30202030 http://dx.doi.org/10.1038/s41598-018-31590-4 |
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