PD-1 has a unique capacity to inhibit allergen-specific human CD4(+) T cell responses

T lymphocytes have a crucial role in initiating and promoting type I allergies. Their responses are tightly regulated by numerous activating and inhibitory signals provided by APCs. Here we have addressed the role of the major coinhibitory receptors PD-1, CTLA-4, BTLA and LAG-3 in allergen-specific...

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Detalles Bibliográficos
Autores principales: Rosskopf, Sandra, Jahn-Schmid, Beatrice, Schmetterer, Klaus Georg, Zlabinger, Gerhard J., Steinberger, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131174/
https://www.ncbi.nlm.nih.gov/pubmed/30201974
http://dx.doi.org/10.1038/s41598-018-31757-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131174/
https://www.ncbi.nlm.nih.gov/pubmed/30201974
http://dx.doi.org/10.1038/s41598-018-31757-z

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