Cargando…

20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats

We hypothesized that vascular actions of 20-hydroxyeicosatetraenoic acid (20-HETE), the product of cytochrome P450 (CYP450)-dependent ω-hydroxylase, potentiate prohypertensive actions of angiotensin II (ANG II) in Cyp1a1-Ren-2 transgenic rats, a model of ANG II-dependent malignant hypertension. Ther...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sedláková, Lenka, Kikerlová, Soňa, Husková, Zuzana, Červenková, Lenka, Chábová, Věra Čertíková, Zicha, Josef, Falck, John R., Imig, John D., Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Krátký, Vojtěch, Červenka, Luděk, Kopkan, Libor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131326/ https://www.ncbi.nlm.nih.gov/pubmed/30054426 http://dx.doi.org/10.1042/BSR20171496

Ejemplares similares

Kidney Response to Chemotherapy-Induced Heart Failure: mRNA Analysis in Normotensive and Ren-2 Transgenic Hypertensive Rats
por: Jíchová, Šárka, et al.
Publicado: (2021)

Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats
por: Kujal, Petr, et al.
Publicado: (2014)

Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats
por: Vacková, Šárka, et al.
Publicado: (2019)

Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats
por: Chábová, Věra Čertíková, et al.
Publicado: (2019)

Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure
por: Vacková, Šárka, et al.
Publicado: (2019)

Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat
por: Kala, Petr, et al.
Publicado: (2020)

Early Renal Vasodilator and Hypotensive Action of Epoxyeicosatrienoic Acid Analog (EET-A) and 20-HETE Receptor Blocker (AAA) in Spontaneously Hypertensive Rats
por: Walkowska, Agnieszka, et al.
Publicado: (2021)

Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats
por: Hrdlička, Jaroslav, et al.
Publicado: (2019)

Renoprotection Provided by Additional Diuretic Treatment in Partially Nephrectomized Ren-2 Transgenic Rats Subjected to the Combined RAS and ET(A) Blockade
por: Vaněčková, Ivana, et al.
Publicado: (2019)

Increased Endogenous Activity of the Renin-Angiotensin System Reduces Infarct Size in the Rats with Early Angiotensin II-dependent Hypertension which Survive the Acute Ischemia/Reperfusion Injury
por: Husková, Zuzana, et al.
Publicado: (2021)

The treatment with trandolapril and losartan attenuates pressure and volume overload alternations of cardiac connexin-43 and extracellular matrix in Ren-2 transgenic rats
por: Sykora, Matus, et al.
Publicado: (2023)

AT(1) receptor blocker, but not an ACE inhibitor, prevents kidneys from hypoperfusion during congestive heart failure in normotensive and hypertensive rats
por: Kratky, Vojtech, et al.
Publicado: (2021)

Epoxyeicosatrienoic Acid Analog and 20-HETE Antagonist Combination Prevent Hypertension Development in Spontaneously Hypertensive Rats
por: Baranowska, Iwona, et al.
Publicado: (2022)

Impaired renal autoregulation and pressure-natriuresis: any role in the development of heart failure in normotensive and angiotensin II-dependent hypertensive rats?
por: Honetschlägerová, Zuzana, et al.
Publicado: (2023)

Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation
por: Kala, Petr, et al.
Publicado: (2021)

The treatment with sGC stimulator improves survival of hypertensive rats in response to volume-overload induced by aorto-caval fistula
por: Gawrys, Olga, et al.
Publicado: (2023)

Sodium Glucose Cotransporter-2 Inhibitors: Spotlight on Favorable Effects on Clinical Outcomes beyond Diabetes
por: Čertíková Chábová, Věra, et al.
Publicado: (2022)

Isovolumic loading of the failing heart by intraventricular placement of a spring expander attenuates cardiac atrophy after heterotopic heart transplantation
por: Pokorný, Martin, et al.
Publicado: (2018)

High Salt Intake Increases Blood Pressure in Normal Rats: Putative Role of 20-HETE and No Evidence on Changes in Renal Vascular Reactivity
por: Walkowska, A., et al.
Publicado: (2015)

Inappropriate activation of the renin-angiotensin system improves cardiac tolerance to ischemia/reperfusion injury in rats with late angiotensin II-dependent hypertension
por: Husková, Zuzana, et al.
Publicado: (2023)

Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension
por: Kala, Petr, et al.
Publicado: (2023)

Effects of Renal Denervation on the Enhanced Renal Vascular Responsiveness to Angiotensin II in High-Output Heart Failure: Angiotensin II Receptor Binding Assessment and Functional Studies in Ren-2 Transgenic Hypertensive Rats
por: Honetschlägerová, Zuzana, et al.
Publicado: (2021)

20-Hydroxyeicosatetraenoic Acid Contributes to the Inhibition of K+ Channel Activity and Vasoconstrictor Response to Angiotensin II in Rat Renal Microvessels
por: Fan, Fan, et al.
Publicado: (2013)

12-hydroxyeicosatetraenoic acid is associated with variability in aspirin-induced platelet inhibition
por: Maskrey, Benjamin H, et al.
Publicado: (2014)

Colección Ren Bonian

Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats
por: Neckář, Jan, et al.
Publicado: (2019)

HISS: Snakemake-based workflows for performing SMRT-RenSeq assembly, AgRenSeq and dRenSeq for the discovery of novel plant disease resistance genes
por: Adams, Thomas M., et al.
Publicado: (2023)

Anti-Fibrotic Potential of Angiotensin (1-7) in Hemodynamically Overloaded Rat Heart
por: Sykora, Matus, et al.
Publicado: (2023)

Ren Zhengfei: lessons from battle
por: Yu, Zhang
Publicado: (2013)

René Turlay (1932-2002)
Publicado: (2002)

Chronologie einer revolution ren Erfindung
Publicado: (2009)

Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target
por: Elshenawy, Osama H., et al.
Publicado: (2017)

Assessment of plasma 12(S)-Hydroxyeicosatetraenoic acid as a biomarker to predict mortality in adults with severe trauma
por: Yang, Liping, et al.
Publicado: (2020)

Game development with Ren'Py: introduction to visual novel games using Ren'Py, TyranoBuilder, and Twine
por: Ciesla, Robert
Publicado: (2019)

The grape powdery mildew resistance loci Ren2, Ren3, Ren4D, Ren4U, Run1, Run1.2b, Run2.1, and Run2.2 activate different transcriptional responses to Erysiphe necator
por: Massonnet, Mélanie, et al.
Publicado: (2022)

20-Hydroxyeicosatetraenoic Acid (20-HETE) Is a Novel Activator of Transient Receptor Potential Vanilloid 1 (TRPV1) Channel
por: Wen, Hairuo, et al.
Publicado: (2012)

Induction of protein catabolism in myotubes by 15(S)-hydroxyeicosatetraenoic acid through increased expression of the ubiquitin–proteasome pathway
por: Whitehouse, A S, et al.
Publicado: (2003)

Differential gene expression mediated by 15-hydroxyeicosatetraenoic acid in LPS-stimulated RAW 264.7 cells
por: Schrimpe, Alexandra C, et al.
Publicado: (2009)

The anti‐inflammatory compound palmitoylethanolamide inhibits prostaglandin and hydroxyeicosatetraenoic acid production by a macrophage cell line
por: Gabrielsson, Linda, et al.
Publicado: (2017)

Ren Zhao: no standard answer to be a doctor
por: Yan, Siying, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cj0c6jsr3nqor4fucobtmf938e