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T cell immunomodulation by clinically used allogeneic human cancellous bone fragments: a potential novel immunotherapy tool

Multipotential stromal cells (MSCs) demonstrate strong immunomodulation capabilities following culture expansion. We have previously demonstrated that human cancellous bone fragments (CBFs) clinically used as viable allografts for spinal fusion have resident MSCs that exhibit T cell immunomodulation...

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Detalles Bibliográficos
Autores principales: El-Sherbiny, Yasser M., El-Jawhari, Jehan J., Moseley, Timothy A., McGonagle, Dennis, Jones, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131386/
https://www.ncbi.nlm.nih.gov/pubmed/30201960
http://dx.doi.org/10.1038/s41598-018-31979-1