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An oligosaccharyltransferase from Leishmania major increases the N‐glycan occupancy on recombinant glycoproteins produced in Nicotiana benthamiana

N‐glycosylation is critical for recombinant glycoprotein production as it influences the heterogeneity of products and affects their biological function. In most eukaryotes, the oligosaccharyltransferase is the central‐protein complex facilitating the N‐glycosylation of proteins in the lumen of the...

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Detalles Bibliográficos
Autores principales: Castilho, Alexandra, Beihammer, Gernot, Pfeiffer, Christina, Göritzer, Kathrin, Montero‐Morales, Laura, Vavra, Ulrike, Maresch, Daniel, Grünwald‐Gruber, Clemens, Altmann, Friedrich, Steinkellner, Herta, Strasser, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131413/
https://www.ncbi.nlm.nih.gov/pubmed/29479800
http://dx.doi.org/10.1111/pbi.12906