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Trimetazidine Attenuates Cardiac Dysfunction in Endotoxemia and Sepsis by Promoting Neutrophil Migration

Aims: Cardiac dysfunction can be a fatal complication during severe sepsis. The migration of neutrophils is significantly impaired during severe sepsis. We sought to determine the role of trimetazidine (TMZ) in regulation of neutrophil migration to the heart in a mouse model of sepsis and endotoxemi...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Wang, Bei, Lai, Jinsheng, Braunstein, Zachary, He, Mengying, Ruan, Guoran, Yin, Zhongwei, Wang, Jin, Cianflone, Katherine, Ning, Qin, Chen, Chen, Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131494/
https://www.ncbi.nlm.nih.gov/pubmed/30233596
http://dx.doi.org/10.3389/fimmu.2018.02015