Urate transporter inhibitor lesinurad is a selective peroxisome proliferator-activated receptor gamma modulator (sPPARγM) in vitro

Gout is the most common arthritic disease in human but was long neglected and therapeutic options are not satisfying. However, with the recent approval of the urate transporter inhibitor lesinurad, gout treatment has experienced a major innovation. Here we show that lesinurad possesses considerable...

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Detalles Bibliográficos
Autores principales: Heitel, Pascal, Gellrich, Leonie, Heering, Jan, Goebel, Tamara, Kahnt, Astrid, Proschak, Ewgenij, Schubert-Zsilavecz, Manfred, Merk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131501/
https://www.ncbi.nlm.nih.gov/pubmed/30202096
http://dx.doi.org/10.1038/s41598-018-31833-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131501/
https://www.ncbi.nlm.nih.gov/pubmed/30202096
http://dx.doi.org/10.1038/s41598-018-31833-4

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