Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS

Altered cellular biomechanics have been implicated as key photogenic triggers in age-related diseases. An aberrant liquid-to-solid phase transition, observed in in vitro reconstituted droplets of FUS protein, has been recently proposed as a possible pathogenic mechanism for amyotrophic lateral scler...

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Detalles Bibliográficos
Autores principales: Antonacci, Giuseppe, de Turris, Valeria, Rosa, Alessandro, Ruocco, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131551/
https://www.ncbi.nlm.nih.gov/pubmed/30272018
http://dx.doi.org/10.1038/s42003-018-0148-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131551/
https://www.ncbi.nlm.nih.gov/pubmed/30272018
http://dx.doi.org/10.1038/s42003-018-0148-x

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