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Differential Dopamine D1 and D3 Receptor Modulation and Expression in the Spinal Cord of Two Mouse Models of Restless Legs Syndrome

Restless Legs Syndrome (RLS) is often and successfully treated with dopamine receptor agonists that target the inhibitory D3 receptor subtype, however there is no clinical evidence of a D3 receptor dysfunction in RLS patients. In contrast, genome-wide association studies in RLS patients have establi...

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Detalles Bibliográficos
Autores principales: Meneely, Samantha, Dinkins, Mai-Lynne, Kassai, Miki, Lyu, Shangru, Liu, Yuning, Lin, Chien-Te, Brewer, Kori, Li, Yuqing, Clemens, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131574/
https://www.ncbi.nlm.nih.gov/pubmed/30233336
http://dx.doi.org/10.3389/fnbeh.2018.00199