Alanine Scanning Mutagenesis of the C-Terminal Cytosolic End of Gpm6a Identifies Key Residues Essential for the Formation of Filopodia

Neuronal membrane glycoprotein M6a (Gpm6a) is a protein with four transmembrane regions and the N- and the C-ends facing the cytosol. It functions in processes of neuronal development, outgrowth of neurites, and formation of filopodia, spines, and synapsis. Molecular mechanisms by which Gpm6a acts i...

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Detalles Bibliográficos
Autores principales: Rosas, Nicolás M., Alvarez Juliá, Anabel, Alzuri, Sofia E., Frasch, Alberto C., Fuchsova, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131581/
https://www.ncbi.nlm.nih.gov/pubmed/30233315
http://dx.doi.org/10.3389/fnmol.2018.00314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131581/
https://www.ncbi.nlm.nih.gov/pubmed/30233315
http://dx.doi.org/10.3389/fnmol.2018.00314

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