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MicroRNA-34b promotes proliferation, migration and invasion of Ewing's sarcoma cells by downregulating Notch1

Ewing's sarcoma is the second most frequent bone and soft tissue sarcoma, which is commonly driven by the Ewing's sarcoma breakpoint region 1-friend leukemia integration 1 transcription factor (EWS-FLI1) fusion gene. Since microRNAs (miRs) can act as either oncogenes or tumor suppressor ge...

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Detalles Bibliográficos
Autores principales: Lu, Qunshan, Lu, Mei, Li, Dong, Zhang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131584/
https://www.ncbi.nlm.nih.gov/pubmed/30106161
http://dx.doi.org/10.3892/mmr.2018.9365