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Neurometabolite Levels in Alcohol Use Disorder Patients During Baclofen Treatment and Prediction of Relapse to Heavy Drinking

Background and Aims: Baclofen, a GABA(B) agonist, is used as a treatment for alcohol dependence. We aimed to examine brain metabolites following administration of baclofen or placebo in alcohol dependent individuals enrolled in a randomized placebo-controlled trial. Methods: Participants included 31...

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Detalles Bibliográficos
Autores principales: Morley, Kirsten C., Lagopoulos, Jim, Logge, Warren, Chitty, Kate, Baillie, Andrew, Haber, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131632/
https://www.ncbi.nlm.nih.gov/pubmed/30233431
http://dx.doi.org/10.3389/fpsyt.2018.00412