Cargando…

Neurometabolite Levels in Alcohol Use Disorder Patients During Baclofen Treatment and Prediction of Relapse to Heavy Drinking

Background and Aims: Baclofen, a GABA(B) agonist, is used as a treatment for alcohol dependence. We aimed to examine brain metabolites following administration of baclofen or placebo in alcohol dependent individuals enrolled in a randomized placebo-controlled trial. Methods: Participants included 31...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morley, Kirsten C., Lagopoulos, Jim, Logge, Warren, Chitty, Kate, Baillie, Andrew, Haber, Paul S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131632/ https://www.ncbi.nlm.nih.gov/pubmed/30233431 http://dx.doi.org/10.3389/fpsyt.2018.00412

Ejemplares similares

Baclofen Response in Alcohol Dependent Patients Concurrently Receiving Antidepressants: Secondary Analysis From the BacALD Study
por: Heng, Sovandara, et al.
Publicado: (2018)

Impaired Decision-Making and Skin Conductance Responses Are Associated with Reward and Punishment Sensitivity in Individuals with Severe Alcohol Use Disorder
por: Logge, Warren B., et al.
Publicado: (2023)

Editorial: Baclofen in the Treatment of Alcohol Use Disorder
por: de Beaurepaire, Renaud, et al.
Publicado: (2019)

The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective
por: de Beaurepaire, Renaud, et al.
Publicado: (2019)

R(+)-Baclofen, but Not S(−)-Baclofen, Alters Alcohol Self-Administration in Alcohol-Preferring Rats
por: Lorrai, Irene, et al.
Publicado: (2016)

Use of Baclofen for Alcohol Use Disorders in the United States
por: Garbutt, James C.
Publicado: (2018)

Sex as a Potential Moderator for Baclofen Response in the Treatment of Alcohol Dependence
por: Morley, Kirsten C., et al.
Publicado: (2022)

Baclofen in the Treatment of Patients With Alcohol Use Disorder and Other Mental Health Disorders
por: Agabio, Roberta, et al.
Publicado: (2018)

Genetic Polymorphisms on OPRM1, DRD2, DRD4, and COMT in Young Adults: Lack of Association With Alcohol Consumption
por: Chung, Patrick, et al.
Publicado: (2020)

A Review of the Potential Mechanisms of Action of Baclofen in Alcohol Use Disorder
por: de Beaurepaire, Renaud
Publicado: (2018)

How to Manage Self-Poisoning With Baclofen in Alcohol Use Disorder? Current Updates
por: Franchitto, Nicolas, et al.
Publicado: (2018)

Pharmacokinetic Studies of Baclofen Are Not Sufficient to Establish an Optimized Dosage for Management of Alcohol Disorder
por: Simon, Nicolas, et al.
Publicado: (2018)

Interaction of Serum Copper and Neurometabolites on Executive Dysfunction in Unmedicated Patients With Major Depressive Disorder
por: Liao, Xiaoxiao, et al.
Publicado: (2021)

Baclofen and the Alcohol Withdrawal Syndrome-A Short Review
por: Cooney, Gary, et al.
Publicado: (2019)

Full-Profile Pharmacokinetic Study of High Dose Baclofen in Subjects With Alcohol Use Disorder
por: Simon, Nicolas, et al.
Publicado: (2018)

Safety Challenges of Using High Dose Baclofen for Alcohol Use Disorder: A Focused Review
por: Rolland, Benjamin, et al.
Publicado: (2018)

Baclofen for the Treatment of Alcohol Use Disorder in Patients With Liver Cirrhosis: 10 Years After the First Evidence
por: Mosoni, Carolina, et al.
Publicado: (2018)

Suppressing Effect of Baclofen on Multiple Alcohol-Related Behaviors in Laboratory Animals
por: Colombo, Giancarlo, et al.
Publicado: (2018)

Baclofen in alcohol use disorder: An analysis of the data provided by the French “Temporary Recommendation for Use” 2014–2017 cohort
por: de Beaurepaire, Renaud, et al.
Publicado: (2022)

The Use of Very High-Doses of Baclofen for the Treatment of Alcohol-Dependence: A Case Series
por: de Beaurepaire, Renaud
Publicado: (2014)

Suppression of Alcohol Dependence Using Baclofen: A 2-Year Observational Study of 100 Patients
por: de Beaurepaire, Renaud
Publicado: (2012)

The Relationship Between Resting Cerebral Blood Flow, Neurometabolites, Cardio-Respiratory Fitness and Aging-Related Cognitive Decline
por: Krishnamurthy, Venkatagiri, et al.
Publicado: (2022)

Preventive Effects of Baclofen but Not Diazepam on Hippocampal Memory and Glucocorticoid Alterations After Prolonged Alcohol Withdrawal in Mice
por: Nadia, Henkous, et al.
Publicado: (2022)

Relationship Between MR Spectroscopy-Detected Glutamatergic Neurometabolites and Changes in Social Behaviors in a Pilot Open-Label Trial of Memantine for Adults With Autism Spectrum Disorder
por: Nair, Neetu, et al.
Publicado: (2022)

Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures
por: Durant, Claire F., et al.
Publicado: (2018)

Baclofen but Not Diazepam Alleviates Alcohol-Seeking Behavior and Hypothalamic–Pituitary–Adrenal Axis Dysfunction in Stressed Withdrawn Mice
por: Rabat, Yolaine, et al.
Publicado: (2019)

The N-Methyl-D-Aspartate Receptor as a Neurobiological Intersection Between Bipolar Disorder and Alcohol Use: A Longitudinal Mismatch Negativity Study
por: Chitty, Kate M, et al.
Publicado: (2015)

Tailored-Dose Baclofen in the Management of Alcoholism: A Retrospective Study of 144 Outpatients Followed for 3 Years in a French General Practice
por: Pinot, Juliette, et al.
Publicado: (2018)

Oral Baclofen Withdrawal Resulting in Hyperactive Delirium: A Case Report
por: Sanders, Benjamin J, et al.
Publicado: (2021)

Right Inferior Frontal Activation During Alcohol-Specific Inhibition Increases With Craving and Predicts Drinking Outcome in Alcohol Use Disorder
por: Grieder, Matthias, et al.
Publicado: (2022)

Drinking alcohol to cope with hyperactive ADHD? Self-reports vs. continuous performance test in patients with ADHD and/or alcohol use disorder
por: Luderer, Mathias, et al.
Publicado: (2023)

Binge Drinking and the Young Brain: A Mini Review of the Neurobiological Underpinnings of Alcohol-Induced Blackout
por: Hermens, Daniel F., et al.
Publicado: (2018)

Incorporating ondansetron and baclofen in alcohol use disorder treatment
por: Ross, Hayley, et al.
Publicado: (2023)

Impact of the COVID-19 Pandemic on Patients With Alcohol Use Disorder and Associated Risk Factors for Relapse
por: Yazdi, Kurosch, et al.
Publicado: (2020)

Baclofen and naltrexone, but not N-acetylcysteine, affect voluntary alcohol drinking in rats regardless of individual levels of alcohol intake
por: Minnaard, A. Maryse, et al.
Publicado: (2020)

Usefulness of Heavy Drinking and Binge Drinking for the Diagnosis of Alcohol Use Disorder
por: Kim, Seong Gu, et al.
Publicado: (2016)

Acamprosate and Baclofen were Not Effective in the Treatment of Pathological Gambling: Preliminary Blind Rater Comparison Study
por: Dannon, Pinhas N., et al.
Publicado: (2011)

Omega-3 for the Prevention of Alcohol Use Disorder Relapse: A Placebo-Controlled, Randomized Clinical Trial
por: Pauluci, Renata, et al.
Publicado: (2022)

Sugars, Alcohol, and Caffeine Intake From Drinks Among Outpatients With Mental Health Disorders in Greece: A Pilot Study
por: Apostolakopoulou, Xenia A, et al.
Publicado: (2022)

A Brief Smoking Cessation Intervention for Heavy Drinking Smokers: Treatment Feasibility and Acceptability
por: Lim, Aaron C., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9k226o360il2legjh7heovj35h