Metformin reverses stem cell-like HepG2 sphere formation and resistance to sorafenib by attenuating epithelial-mesenchymal transformation

Cancer stem cells (CSCs) have been reported to be associated with the recurrence and drug resistance of liver cancer. In the present study, stem cell-like HepG2 cell spheres were enriched using stem cell conditioned culture medium. As expected, stem-like HepG2 cell spheres exhibited increased resist...

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Detalles Bibliográficos
Autores principales: Feng, Yan, Guo, Xing, Huang, Xinping, Wu, Manya, Li, Xin, Wu, Shushu, Luo, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131649/
https://www.ncbi.nlm.nih.gov/pubmed/30106125
http://dx.doi.org/10.3892/mmr.2018.9348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131649/
https://www.ncbi.nlm.nih.gov/pubmed/30106125
http://dx.doi.org/10.3892/mmr.2018.9348

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