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A natural ent-kaurane diterpenoid induces antiproliferation in ovarian cancer cells via ERK1/2 regulation and inhibition of cellular migration and invasion

Ovarian cancer is one of the most common causes of female mortalities from gynecological tumors. An ent-kaurane diterpenoid compound CRT1 (ent−18-acetoxy-7β-hydroxy kaur-15-oxo-16-ene), mainly isolated from the Vietnamese herb Croton tonkinesis has been used in folk medicine in Vietnam for cancer tr...

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Detalles Bibliográficos
Autores principales: Lee, Jin Sun, Lee, Myung Sun, Cha, Eun Young, Thuong, Phuong Thien, Sul, Ji Young, Park, Jun Beom, Ko, Young Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131655/
https://www.ncbi.nlm.nih.gov/pubmed/30106144
http://dx.doi.org/10.3892/mmr.2018.9377