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In vitro suppression of inflammatory cytokine response by methionine sulfoximine

BACKGROUND: The glutamine synthetase inhibitor methionine sulfoximine (MSO), shown previously to prevent death caused by an inflammatory liver response in mice, was tested on in vitro production of cytokines by mouse peritoneal macrophages triggered with lipopolysaccharide (LPS). RESULTS: MSO signif...

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Detalles Bibliográficos
Autores principales: Peters, Tyler J., Jambekar, Amruta A., Brusilow, William S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131744/
https://www.ncbi.nlm.nih.gov/pubmed/30214381
http://dx.doi.org/10.1186/s12950-018-0193-8