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Levetiracetam enhances the temozolomide effect on glioblastoma stem cell proliferation and apoptosis

BACKGROUND: Glioblastoma multiforme (GBM) is a highly aggressive brain tumor in which cancer cells with stem cell-like features, called cancer stem cells (CSCs), were identified. Two CSC populations have been previously identified in GBM, one derived from the GBM area called enhanced lesion (GCSCs)...

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Detalles Bibliográficos
Autores principales: Scicchitano, Bianca Maria, Sorrentino, Silvia, Proietti, Gabriella, Lama, Gina, Dobrowolny, Gabriella, Catizone, Angela, Binda, Elena, Larocca, Luigi Maria, Sica, Gigliola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131782/
https://www.ncbi.nlm.nih.gov/pubmed/30214378
http://dx.doi.org/10.1186/s12935-018-0626-8