Cargando…

Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol

BACKGROUND: Inflammation has been proposed to contribute to the decline in adult hippocampal neurogenesis. Proinflammatory cytokines activate transcription of chemokine growth-regulated oncogene α (Gro1) in human and murine hippocampal neuronal progenitor cells (NPC). The goal of this study was to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Zonis, Svetlana, Breunig, Joshua J., Mamelak, Adam, Wawrowsky, Kolja, Bresee, Catherine, Ginzburg, Nadiya, Chesnokova, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131894/
https://www.ncbi.nlm.nih.gov/pubmed/30201019
http://dx.doi.org/10.1186/s12974-018-1298-y