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Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol
BACKGROUND: Inflammation has been proposed to contribute to the decline in adult hippocampal neurogenesis. Proinflammatory cytokines activate transcription of chemokine growth-regulated oncogene α (Gro1) in human and murine hippocampal neuronal progenitor cells (NPC). The goal of this study was to i...
Autores principales: | Zonis, Svetlana, Breunig, Joshua J., Mamelak, Adam, Wawrowsky, Kolja, Bresee, Catherine, Ginzburg, Nadiya, Chesnokova, Vera |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131894/ https://www.ncbi.nlm.nih.gov/pubmed/30201019 http://dx.doi.org/10.1186/s12974-018-1298-y |
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