Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity

Expression quantitative trait loci (eQTLs) identified using tumor gene expression data could affect gene expression in cancer cells, tumor-associated normal cells, or both. Here, we have demonstrated a method to identify eQTLs affecting expression in cancer cells by modeling the statistical interact...

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Detalles Bibliográficos
Autores principales: Geeleher, Paul, Nath, Aritro, Wang, Fan, Zhang, Zhenyu, Barbeira, Alvaro N., Fessler, Jessica, Grossman, Robert L., Seoighe, Cathal, Stephanie Huang, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131897/
https://www.ncbi.nlm.nih.gov/pubmed/30205839
http://dx.doi.org/10.1186/s13059-018-1507-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131897/
https://www.ncbi.nlm.nih.gov/pubmed/30205839
http://dx.doi.org/10.1186/s13059-018-1507-0

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