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Quantification of variation and the impact of biomass in targeted 16S rRNA gene sequencing studies

BACKGROUND: Recent advances in sequencing technologies and bioinformatics tools have allowed for large-scale microbiome studies that are rapidly advancing medical research. However, small changes in technique or analysis can significantly alter the results and lead to conflicting findings. Quantifyi...

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Detalles Bibliográficos
Autores principales: Bender, Jeffrey M., Li, Fan, Adisetiyo, Helty, Lee, David, Zabih, Sara, Hung, Long, Wilkinson, Thomas A., Pannaraj, Pia S., She, Rosemary C., Bard, Jennifer Dien, Tobin, Nicole H., Aldrovandi, Grace M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131952/
https://www.ncbi.nlm.nih.gov/pubmed/30201048
http://dx.doi.org/10.1186/s40168-018-0543-z